| ▲ Research has shown that a new cell therapy has been developed that can remove glioblastoma and act as a cancer vaccine to prevent tumor recurrence. (Photo = DB) |
[메디컬투데이=최재백 기자] A new cell therapy that can remove glioblastoma and act as a cancer vaccine to prevent tumor recurrence has been developed.
A study published in the journal ‘Science Translational Medicine’ found that a new cell therapy that can remove glioblastoma and act as a cancer vaccine to prevent tumor recurrence has been developed.
Researchers at Brigham and Women’s Hospital tested the efficacy of an experimental cell therapy in a mouse model of glioblastoma. The research team said they came up with a simple idea to transform cancer cells into cancer-removing cells and vaccines.
They aimed to use genetic engineering techniques to turn cancer cells into tumor-destroying treatments and stimulate the immune system to eliminate primary tumors as well as prevent cancer.
According to the research team, the new cell therapy uses live tumor cells, unlike most cancer vaccines that use inactive tumor cells.
The research team reported that ‘therapeutic tumor cells (ThTC)’, which engineered tumor cells to secrete cell death and immune modulatory substances, showed the effect of removing glioblastoma tumors formed in mice.
They anticipate that the new cell therapy could be used to treat cancers other than glioblastoma, and predict that a cancer vaccine with a similar principle will be available within 3 to 5 years.
Experts evaluated that this study manipulated living cancer cells to directly kill tumor cells, activate the immune system, and reduce tumor immunosuppression, thereby promoting the anticancer action of the immune system.
Medical Today Reporter Jaebaek Choi ([email protected])
[저작권자ⓒ 메디컬투데이. 무단전재-재배포 금지]