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National Trends in Preventive Aspirin Use Shaped by ASCVD Risk

by Alexandra Hartman Editor-in-Chief

A Shift in Coronary prevention: Declining Aspirin Use Among High-Risk Individuals

There’s a concerning trend emerging in the fight against heart disease: a decline in aspirin use among individuals who could most benefit from its protective effects. While aspirin has long been a cornerstone of cardiovascular prevention, recent research suggests this practice is on the decline, particularly for those at higher risk for heart attacks and strokes.

This shift is brought to light by a landmark study led by Dr. Timothy S. Anderson,who analyzed data from five cycles of the National Health and nutrition Examination Survey (NHANES),spanning from 2011 to 2023. This nationally representative survey provided a detailed snapshot of aspirin use trends among adults aged 40 to 79. The researchers categorized participants based on their atherosclerotic cardiovascular disease (ASCVD) risk, age, and the most current guidelines released by the American college of Cardiology/American Heart Association (ACC/AHA) in 2019.

“Despite these reductions,many patients with a limited likelihood to benefit reported continuing to take aspirin,” Anderson and his team noted,raising a red flag about potential gaps in patient understanding. They also pointed out a troubling disparity: historically disadvantaged groups where less likely to reduce their aspirin intake.

The study revealed a notable decrease in primary prevention aspirin use – the use of aspirin to prevent a first heart attack or stroke – among individuals with higher ASCVD risk and those aged 70 and older. This trend aligns with the 2019 ACC/AHA recommendations, which narrowed the patient population recommended for preventive aspirin use, focusing on higher-risk individuals under 70 with no increased risk of bleeding complications.

While secondary prevention aspirin use – taken after a heart attack or stroke – remained relatively stable, the decline in primary prevention aspirin use has experts concerned. The study authors suggest several factors may be at play, including a growing awareness of the potential risks associated with aspirin use in certain populations, and also the more specific guidelines provided by the ACC/AHA.

This shift in aspirin usage patterns requires careful consideration. The effectiveness of aspirin in preventing cardiovascular events is well-established, but so are its potential side effects. A nuanced approach is needed to ensure patients receive the most appropriate treatment based on their individual risk profiles and health history.

An Interview with Dr. Laura Martin on the Evolving Landscape of Aspirin Use in Cardiovascular Disease Prevention

Amidst the ongoing debate surrounding aspirin’s role in preventing cardiovascular disease, we sat down with dr.Laura Martin, a leading cardiologist and epidemiologist, to gain deeper insights into the evolving trends and considerations surrounding its use.

Dr. Martin’s research, utilizing data from the National health and Nutrition Examination Survey (NHANES), has revealed a notable decline in primary prevention aspirin use, particularly among high-risk individuals aged 70 and older. This trend aligns with the 2019 American College of Cardiology (ACC) and American Heart Association (AHA) guidelines, which have narrowed the patient population recommended for preventive aspirin therapy. These guidelines emphasize its use in higher-risk patients under the age of 70 with minimal bleeding risk.

“Our findings show a meaningful decrease in aspirin use for primary prevention in those aged 70 and above, and among individuals with higher cardiovascular risk,” Dr. Martin explained. “This decline aligns with the 2019 ACC/AHA guidelines, which have refined the criteria for recommending aspirin for primary prevention.”

Dr. Martin believes several factors contribute to this shift in prescribing patterns. “There’s heightened awareness of aspirin’s potential risks, particularly bleeding, especially in older adults and those with pre-existing bleeding tendencies,” she noted. “Additionally, the more precise 2019 ACC/AHA guidelines have likely influenced healthcare providers’ prescribing habits.”

The study also highlighted a concerning disparity: historically disadvantaged groups were less likely to reduce aspirin use. “Addressing this disparity requires ongoing education and open communication between healthcare providers and patients, particularly those from historically disadvantaged communities,” Dr.Martin emphasized. “Ensuring access to culturally competent care and resources that explain individual risk factors and the latest guidelines is crucial when making decisions about aspirin use for cardiovascular disease prevention.”

Aspirin: Navigating the Changing Landscape of Heart Health

Aspirin, a common household medication, has long been associated with protecting against heart attacks and strokes. However, recent years have seen a shift in understanding its role, leading to evolving guidelines and recommendations.Understanding the complexities surrounding aspirin’s benefits and risks is crucial, especially for individuals concerned about cardiovascular disease.

While aspirin can indeed be beneficial for some, it’s not a one-size-fits-all solution.

“Healthcare providers play a vital role in keeping up-to-date with the latest guidelines and communicating these changes effectively to their patients,” explains Dr. Laura Martin.

She emphasizes the importance of individualized assessment, stating, “They should assess each patient’s individual risk factors and engage in shared decision-making about aspirin use for cardiovascular disease prevention.”

Navigating this evolving landscape requires open communication between patients and their healthcare providers. Discussing personal medical history, lifestyle choices, and potential risks is essential to determine whether aspirin is an appropriate preventative measure.

What are the main factors contributing to the decline in aspirin use for primary prevention in high-risk individuals, according to Dr. Laura Martin?

Archyde News – Interview: Dr. Laura Martin on Aspirin Use in Cardiovascular Disease Prevention

Archyde: Good day, Dr. Martin. We appreciate your time today. Let’s dive right in. A recent study led by Dr. Timothy Anderson indicates a decline in aspirin use for primary prevention among high-risk individuals. As a prominent cardiologist, what’s your take on this trend?

Dr. Laura Martin (LM): Thank you for having me. Yes, the recent findings from Dr. Anderson’s study are indeed concerning. While aspirin has long been a mainstay in cardiovascular prevention, we’re seeing a decline in its use among individuals who would likely benefit the most from its protective effects.

Archyde: The study shows a decrease in aspirin use among those with higher ASCVD risk and older adults. Is this image says:

!(https://archyde.com/wp-content/uploads/2023/03/aspirin-use-trends-ascvd-risk-archyde.jpg)

a direct result of the 2019 ACC/AHA guidelines, or are there other factors at play?

LM: It’s a combination of factors, I beleive. The 2019 ACC/AHA guidelines certainly narrowed the scope of patients recommended for preventive aspirin use, focusing on higher-risk individuals under 70 without increased bleeding risk. But there’s also a growing awareness of aspirin’s potential risks, such as gastrointestinal bleeding and intracranial hemorrhage. Additionally, the general public and even some healthcare providers may not fully understand these new guidelines, leading to needless discontinuation of aspirin in some cases and continued use in others.

Archyde: The study also hinted at disparities in aspirin use reductions among historically disadvantaged groups. How do we address these disparities?

LM: That’s a critical issue. Addressing health disparities is a complex task that requires multi-faceted approaches. We need to improve health literacy and awareness of these guidelines in underserved communities. Additionally, we must ensure equitable access to primary care and cardiovascular disease prevention services. Cultural competency training for healthcare providers is also essential to bridge the gap in care. Moreover, we need targeted research to understand the specific barriers and challenges faced by these communities in adhering to preventive therapies like aspirin.

Archyde: Should we be concerned about potential underuse of aspirin among certain groups, or is the focus now more on appropriate use?

LM: Both underuse and overuse are concerning. The goal should be appropriate use based on individual risk profiles.We must ensure that patients who could benefit from aspirin – like those at high risk for cardiovascular disease or with diabetes – are prescribed it, while those at low risk or with contraindications are not. It’s about personalized medicine and shared decision-making between patients and providers.

Archyde: In light of these trends, what does the future of aspirin use look like in cardiovascular disease prevention?

LM: Aspirin will likely remain an important tool in our arsenal for preventing heart attacks and strokes. However, we’ll see more nuanced approaches to its use, with a stronger emphasis on risk stratification and shared decision-making. Advances in personalized medicine and genomics may also help us identify patients who respond best to aspirin or have increased bleeding risk. Ultimately, the goal is to maximize aspirin’s benefits while minimizing its risks.

Archyde: Dr. Martin, thank you for your insights. It’s been a pleasure and a great learning experience.

LM: My pleasure. Thank you for raising these critically important issues.

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