Postpartum Prolapse and Infarction of a Submucosal Leiomyoma: A Case Report

A 33-year-old woman experienced the rare postpartum prolapse of an infarcted submucosal leiomyoma following a forceps-assisted delivery. Initially misdiagnosed as potential retained products of conception due to localized bleeding and pain, the mass was identified via MRI at seven weeks postpartum and successfully removed, highlighting the diagnostic challenges of uterine fibroids during the puerperium.

Clinical Insights for Postpartum Recovery

  • Fibroid Migration: Uterine leiomyomas (fibroids) can shift position or become pedunculated (attached by a stalk) as the uterus shrinks after birth, potentially leading to cervical prolapse.
  • Diagnostic Mimicry: Symptoms like bleeding and pain in the weeks after delivery are often attributed to infection or retained placenta; however, a prolapsing fibroid can present with identical clinical features.
  • Imaging Necessity: When ultrasound findings remain ambiguous, contrast-enhanced MRI is a critical tool to distinguish between retained tissue and degenerating leiomyomas before attempting surgical intervention.

Tracking Fibroid Movement Through Serial Imaging

The patient’s clinical history, as documented in the case report published by Cureus, illustrates a complex diagnostic timeline. Following a forceps-assisted delivery, the patient presented on day five with low-grade fever and secondary postpartum hemorrhage. While clinicians initially suspected a puerperal infection—an inflammation of the reproductive tract following childbirth—ultrasound imaging revealed a 79 mm anterior wall fibroid alongside a heterogeneous area in the fundal cavity. This raised concerns about retained products of conception, a common complication where placental tissue remains in the uterus.

The situation evolved over the following seven weeks. Subsequent transvaginal ultrasound showed the fibroid had vanished from its original position in the uterine wall, while a new 44 mm mass appeared at the cervix. Contrast-enhanced MRI confirmed that this mass was the original fibroid, now attached by a stalk and prolapsing through the cervical os. This movement is consistent with uterine involution, the process by which the uterus returns to its pre-pregnancy size, which can physically displace pedunculated tumors.

Distinguishing Infarction from Carneous Degeneration

While the MRI suggested “carneous degeneration”—a process where the fibroid’s blood supply is compromised leading to red, fleshy tissue—the histopathological analysis confirmed “infarction.” These terms describe different stages of tissue death due to ischemia, or lack of blood flow. In this patient, the pedunculation of the fibroid likely caused the stalk to stretch or twist, cutting off the blood supply. This clinical progression mirrors a separate case reported in the National Center for Biotechnology Information (NCBI), where a large pedunculated fibroid was similarly managed 35 days postpartum, emphasizing that such cases, while rare, represent a distinct subset of obstetric complications.

Feature Clinical Finding
Patient Age 33 years
Initial Diagnosis (Day 5) Presumed puerperal infection/retained products
Primary Intervention Vaginal removal and endometrial sampling

Defer Surgical Evacuation If Fibroids Are Suspected

It is critical to note that surgical evacuation of the uterus (such as dilation and curettage) should be deferred if a large fibroid is suspected, as the presence of the mass can make instrumentation hazardous and increase the risk of uterine perforation. A pelvic exam and advanced imaging are required to confirm the location and attachment of the fibroid before any manual or surgical removal is attempted.

Future Management of Postpartum Leiomyomas

The successful handling of this case shows how critical serial imaging is when postpartum recovery doesn’t follow the usual pattern. By identifying the mass as an infarcted leiomyoma rather than retained placental tissue, the clinical team avoided unnecessary or dangerous invasive procedures. This case highlights how postpartum physiological changes can sharply change the behavior of benign gynecological tumors. The patient recovered well following the vaginal removal of the mass, confirming that timely, evidence-based intervention is effective for managing these complex presentations.

References

  • NCBI: Case Report on Transvaginal Manual Removal of a Postpartum Fibroid

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Priya Deshmukh - Senior Editor, Health

Priya Deshmukh Senior Editor, Health Deshmukh is a practicing physician and renowned medical journalist, honored for her investigative reporting on public health. She is dedicated to delivering accurate, evidence-based coverage on health, wellness, and medical innovations.

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