2023-06-17 07:18:00
On June 17, 2023 Prof. Dr. Teerawat Hemajutha or “Doctor Theerawat” Director of Emerging Diseases Health Science Center Faculty of Medicine Chulalongkorn University A private Facebook post states that
- Too Much Vitamin B6, Nerve Inflammation
general practitioners, especially psychiatrists andnervous system Become suspicious, observe and observe. abnormality ofnervewhich cannot be explained by the absence of chronic congenital disease It’s not emaciated, lacking food, or having liver disease, but instead having nerve symptoms. In the form of numbness, burning sensation along the toes and toes of the hands. Until there is pain in the bones until the muscles are weak. and in some cases, muscle spasms Abnormal balance, staggering, and, until now, frequent urination, day and night, have been reported. and finally unable to urinate (Dose used at 10 mg per day for three years) and symptoms improved after discontinuation. for no other reason And there are more and more reports in neurological journals and toxicology centers.
That is, the effect or side effect that occurs from the supplement.vitamin B complex with the amount of Vitamin B6 in high doses by the doctor who prescribes it or the person who eats it may not know because it is a mixture contained in vitamins, minerals which are commonly sold and consumed by many brands, without warning of possible side effects Because in the early stages It’s unclear what size it should be. Which is considered a water soluble vitamin. and can be excreted
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the size ofmultivitamin with B 6 Higher doses of 10 to 25 milligrams per day are needed as a therapeutic dose if necessary, such as when taking isoniazid for tuberculosis and when side effects of isoniazid occur until seizures occur. climb and in pregnant women with severe vomiting (hyperemesis gravidarum) and in patients with abnormal conditions. Nutrition provides a high level of vitamins. decrease and cause neurological symptoms as well
In addition to isoniazid, there are other drugs such as cycloserine penicillamine. The Parkinson’s disease drug levodopa lowers vitamin B6 levels, and B6 is also used to treat magnesium deficiency.
for other reasons That must be supplemented with vitamin B 6 because in the elderly. Especially with congenital disease People often don’t get enough B6 nutrients, with B6 found in meat, liver, fish, beans and lentils. and foods that have been processed, stored, and cooked will reduce their B6 content by 10 to 50%.
symptoms of deficiency will be the same Vitamin B6 Too much to the point that it may cause confusion as to what exactly is caused. This may require testing of vitamin levels. in the blood together with along with other causes such as neurological symptoms Especially with numbness and burning caused by diabetes, underactive thyroid gland, HIV infection. infection with certain bacteria until syphilis Immune disease disease that has been created Abnormal bone marrow protein (monoclonal gammopathy), lymphoma, and drug toxicity, including cancer chemotherapy, heavy metal poisoning, pesticides organophosphorus
The usual daily dose of vitamin B6 is 0.5 to 1 mg in children, 1.3 mg in adolescents and adults, 1.7 mg in men over 50, and 1.7 mg in women over 50. size 0.5 milligrams
in general, in order not to complicate for adults women or men The overall dosage is 1.9 milligrams per day. For people who are really elderly The dosage can be higher but should not exceed 10 mg per day.
The mechanism of vitamin B6 toxicity is also dose dependent. and duration of eating It is possible that with enzyme inhibition pyridoxal-5-phosphate dependent enzymes
In many countries such as Australia The use of vitamin B complex and B6 has been closely monitored, with the dosage of vitamin B6 in all products reduced from 200 mg daily to no more than 100 mg daily in adults. and reduced size in children
As of August 5, 2022, for example, of the 32 reported cases, 22 were confirmed with elevated blood levels. and 21 took vitamin B6 at a daily dose of 50 mg or less. In nine cases, a combination of products containing vitamin B6 was found to have been used.
and with such side effects All products containing doses of B6 above 10 mg per day must be clearly labeled. about the dangers that may arise from nerve inflammation As announced on October 4, 2022 (Australian Government. Department of Health and Aged Care/Therapeutic Goods Administration).
For the United States, the supplementVitamin B6 Especially in the elderly, it will be in a dose of no more than 50 to 100 milligrams per week (American Journal of Therapeutics, Nov/Dec 2022).
At this point, don’t be afraid. Too many vitamins, because these vitamins It is necessary for the body to grow. and repair the worn parts and in the food we eat every day By having to eat healthy food, but in elderly people, pregnant people or in abnormal conditions or use certain drugs together Vitamin supplements may be needed. but must look at the right size And must not add too much even though there is no need at all
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