“Sex Reversal Syndrome: Understanding the Causes and Treatment”

2023-05-25 14:13:55

A couple in Wenzhou City, Zhejiang Province, China has been married for 6 years, but they have been unable to conceive a child. An examination found that there was no sperm in the husband’s semen. (Picture/Pixabay)

A couple in Wenzhou City, Zhejiang Province, China, had been married for 6 years but could not conceive a child. The anxious wife and her husband came to the Reproductive Medicine Center of the First Affiliated Hospital of Wenzhou Medical University together. After detailed interrogation, the doctor found that apart from working overtime, her husband had a regular daily life, and his married life was normal. But the results of the husband’s semen analysis surprised the couple. It turned out that there was no sperm in his semen.

Although this husband has male primary and secondary sexual characteristics, the result of chromosome examination showed “46XX”, which is clinically known as “sex reversal syndrome”. (Picture / flip from Weibo)

According to the “Chengdu Business Daily” report, after careful interrogation and testing, the doctor found that the man’s semen was “empty” and no sperm was found. This result surprised and confused the couple. The doctor arranged a more detailed examination, hoping to find out the cause of the disease. It turned out that although the husband had male primary and secondary sexual characteristics, the result of the chromosome examination showed “46XX”, which is clinically called “46XX”. “Sex Reversal Syndrome”, also known as “Klinefelter’s Syndrome”, this condition genetically means that “he” is not a man.

General clinical symptoms, male infants after birth to early childhood, usually in addition to testicular agenesis, such as small or hidden testes, short penis leading to sexual dysfunction, gynecomastia, beard, armpit hair and pubic hair are scarce or absent, no Adam’s apple, skin More delicate, no sperm after ejaculation, body like a woman, but in some cases the symptoms are not obvious. Due to the long-term low male hormones, in addition to the lack of sperm or no sperm, it will also cause muscle weakness, osteoporosis, anemia, loss of libido, etc.

After the husband’s symptoms were identified, doctors administered chemotherapy and recommended surgery to restructure his reproductive organs. After a period of treatment, the situation has been greatly improved. The couple then welcomed their first child, and the birth of the baby filled the family with laughter.

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