single-cell RNA sequencing

How High Glucose Triggers Inflammation in Diabetic Kidney Disease

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Diabetic kidney disease affects approximately 40% of individuals with diabetes, frequently advancing to kidney failure due to high blood pressure. Recently, researchers utilizing advanced stem cell-based human kidney organoids discovered … Read More

Single-Cell Analysis Reveals Immune Shifts in Pulmonary Sarcoidosis

Single-Cell Analysis Reveals Immune Shifts in Pulmonary Sarcoidosis

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Researchers at National Jewish Health and partner institutions have mapped the cellular architecture of pulmonary sarcoidosis using single-cell RNA sequencing and spatial transcriptomics, revealing hybrid pro-inflammatory and pro-fibrotic macrophages, altered … Read More