2023-07-15 20:00:00
Written by Nahir Abdel Nabi, Saturday, July 15, 2023 11:00 PM
The results of a scientific study conducted by Forsythe Institute scientists showed how dangerous gingivitis is to the brain, as the Journal of Neuroinflammation indicates that oral cavity diseases can lead to Alzheimer’s disease.
Previous studies have linked periodontitis to an inflammatory response in the brain. In this study, the researchers focused on the changes that can occur in brain cells when pathogenic bacteria are present in the oral cavity. For this, they studied microglia, white blood cells that remove associated amyloid plaques. Alzheimer’s disease.
The researchers conducted experiments on laboratory mice, during which they followed the bacteria in the oral cavity that cause gingivitis. They confirmed that these bacteria had reached the brain, and then identified the glial cells in the brain that were exposed to the oral cavity bacteria.
And it became clear to the researchers, that the presence of pathogenic bacteria in the oral cavity leads to an overactivity of glial cells, which stimulates nerve inflammation and prevents the destruction of amyloid plaques, in other words, the presence of inflammation in the gums allows microorganisms to reach the bloodstream and reach other parts of the body, including the brain. .
According to the researchers, this discovery allows for the creation of more effective strategies for the prevention and treatment of Alzheimer’s disease, that is, to prevent neurodegeneration, it is very important to control the inflammation of the oral cavity associated with gum disease.
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