When Everyday is Groundhog Day: Unraveling the Mystery of Chronic Déjà Vu in Alzheimer’s Disease – A Study

2023-05-25 14:00:00

The permanent impression of having already lived what he is going through, this is what an octogenarian suffering from an extremely rare form of Alzheimer’s disease felt. Doctors come back to his case in an unpublished study.

The feeling of “déjà-vu”, this fleeting impression of having already experienced a scene that one is experiencing, is very common. This error in the memory circuitry in our brains has long been explained by science. But the lingering feeling of continuing to relive the same things over and over again is rarer. The particularly interesting case of an 80-year-old man who said relive the same day over and over again was first studied in detail by medical specialists in Australia and London, who are publishing their findings in the journal this month BMJ Cas Reports. According to their findings, this man suffered from a rare symptom of Alzheimer’s disease.

“My television always says the same thing”

“Everywhere I go, the same people are on the side of the road, the same cars behind me with the same people inside… They wear the same clothes, the same bags, say the same things. Nothing is new”described this patient in an attempt to explain what was happening to him, according to Live Science. The senior also complains to the manufacturer of its e-reader because‘he thought she always displayed the same thingand contacted a technician about his television which always broadcast the same information.

The déjà vu that he said he felt was therefore much more than a passing, occasional sensation, which moreover recurs more often in people with certain forms of epilepsy. Here it is a DVRC, in English, “already lived with recollective confabulation”, according to the researchers. It would be a consequence of a neurodegenerative disease, in particular Alzheimer’s disease. Two years after the start of this “endless day”several analyzes have enabled doctors to identify the biomarkers traditionally associated with this pathology. “This case suggests that deficits of both memory and metacognition (awareness of one’s knowledge) are responsible”, explains the study.

A rare case of hippocampal dysfunction

The patient seemed consider two different stories like being one. According to the report, which indicates that a handful of similar cases had already been described by doctors in people suffering from Alzheimer’s or dementia, it could be a disorder of theseahorse. This part of the brain is indeed responsible for making memories. It is he who malfunctions, temporarily, when you have a feeling of deja-vu. “The feeling of deja vu is when the hippocampus makes a small mistake when it receives information from the eyes or the ears. It is no longer in a position to collect what it sees but will rather seek a memory in the cortex. it synchronizes the scene with our memories rather than encoding what we are experiencingdescribed Patrick Chauvel, neurologist at the Timone hospital, in Marseille, in this article.

But this is the first time that a patient with chronic deja vu has been monitored so closely. “CRDV, although rare, is a fascinating phenomenon that provides a unique perspective on memory and the mechanisms of dementia”, according to the researchers. Unfortunately, four years after the onset of her symptoms, his cognitive state deteriorated, despite medical treatment. Because despite numerous medical advances in this area, there is no still no cure for Alzheimer’s disease. The octogenarian, however, continues to live independently at home, although his permanent impressions of deja vu remain “embarrassing” for him on a daily basis.

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