[의학신문·일간보사=이재원 기자] Even with the same obesity, the more metabolically unhealthy, the higher the risk of hot flashes and night sweats, which are menopausal symptoms, a new study found.
Sungkyunkwan University of Medicine Kangbuk Samsung Hospital (President Shin Hyun-cheol) Data Management Center Professor Seung-ho Ryu and Yoo-su Jang research team conducted a study on 4,600 premenopausal women aged 42 to 52 years who visited the Gangbuk Samsung Hospital general health center between 2014 and 2018. analysis was carried out.
The research team first classified the groups according to body fat percentage, one of the indicators of obesity. As a result, menopausal symptoms increased 1.42 times in mild obesity (30~34.9%) compared to normal body fat percentage (<25%). Moderate obesity (≥35%) had a 1.6-fold increase in menopausal symptoms.
Next, the research team divided and compared the effect of obesity according to body fat percentage according to the presence or absence of metabolic disease indicators such as blood pressure and blood sugar.
In metabolically healthy individuals, there was a 1.34-fold increased risk of menopausal symptoms in patients with moderate body fat relative to normal body fat percentage (≥35%), and those with metabolically healthy patients with moderate body fat relative to normal body fat percentage (≥35%) The risk of developing menopausal symptoms increased by 3.61 times.
A metabolically healthy state is defined as a case in which blood sugar, blood pressure, triglyceride, high-density cholesterol, and insulin resistance indicators are all normal.
According to these results, there is an interaction between body fat percentage and metabolic health level, and when body fat obesity and metabolic unhealthy conditions are accompanied, the occurrence of vasomotor symptoms (hot flashes and night sweats), which are typical menopausal symptoms, is much higher. could confirm that
Kangbuk Samsung Hospital Data Management Center Professor Ryu Seung-ho said, “There have been studies on the relationship between obesity and menopausal symptoms in menopausal women, but this is the first study to determine the effect of obesity with metabolic disease on menopausal symptoms.” emphasized.
Professor Jang Yu-soo of the Data Management Center at Kangbuk Samsung Hospital said, “Pre-menopausal women maintain a normal body fat percentage and improve their metabolism in order to prevent the deterioration of the quality of life caused by menopausal symptoms and the development of chronic diseases such as cardiovascular diseases. It is important to stay healthy.”
Meanwhile, this study was supported by the National Institute of Health and Training of the Korea Centers for Disease Control and Prevention as part of a prospective research project to identify risk factors for chronic diseases in menopausal women. .