2023-11-01 04:13:29
Breast cancer patients have a higher risk of developing cancer than stomach, colon, and lung cancer.
Entered 2023.11.01 13:13 Views 1 Entered 2023.11.01 13:13 Views 1
Shingles usually causes a blistering rash on one side of the body within a few days or weeks. [사진= 게티이미지뱅크]According to the Health Insurance Review and Assessment Service’s healthcare big data open system, as of 2022, the proportion of women among all shingles patients occurring annually is 61%, which is higher than that of men. In terms of age, those in their 50s or older were found to account for approximately 64% of the total (22.3% in their 50s, 23.9% in their 60s, 12.5% in their 70s, and 5.9% in their 80s or older). The median age at the time of cancer diagnosis among breast cancer patients in Korea is 52.3 years. Those over 50 years old, women, and breast cancer patients who fall into all cancer categories are among those vulnerable to shingles.
For cancer patients, efforts must be made to manage their health, prevent disease, and prevent recurrence not only during treatment but also after treatment has ended. One of the representative infectious diseases that threaten these people is shingles. Several studies have confirmed that breast cancer patients have a high risk of developing shingles. According to a study at the University of New South Wales in Australia, the risk of developing shingles in patients diagnosed with breast cancer was 1.38 times higher than that of the general population. Another study that looked at the risk of shingles by cancer type found that the risk of shingles in breast cancer patients was higher than in patients with stomach, colon, and lung cancer. In a study conducted on patients with solid cancers, including breast cancer, receiving immunosuppression or chemotherapy, it was confirmed that the incidence of shingles in cancer patients was two times higher than in the overall population.
Shingles usually causes a blistering rash on one side of the body within a few days or weeks. It causes fever similar to a cold, pain like an electric shock, and a stinging or burning sensation. If not treated in time, you may suffer from serious complications such as ‘postherpetic neuralgia’, which can last for several weeks to years even after the blisters subside.
64% of shingles patients are in their 50s or older… Occurs more often in women than men
Experts analyze that immunocompromised people, including cancer patients, have more and wider shingles, and can last for a longer period of time, than general patients. Shingles can also manifest as hemorrhagic shingles, in which blisters fill with blood. The likelihood of complications or recurrence due to shingles, such as postherpetic neuralgia (PHN), viremia, pneumonia, and hepatitis, is higher than that of the general population.
If you have breast cancer (patients or those diagnosed with the disease), it is recommended to get the preventive vaccine along with a balanced diet, regular exercise, and sufficient sleep to actively prevent shingles in advance. Professor Kyeong-Hae Jeong of the Department of Oncology at Seoul Asan Medical Center said, “Cancer patients have a high risk of developing shingles not only during treatment but also after treatment because their immune system can be weakened due to chemotherapy and radiation treatment. Shingles is more common in women than in men. “It has been reported that it occurs,” he said. “If you are a breast cancer patient, which occurs frequently in women after middle age, you should make more active efforts to prevent shingles.”
There are two types of shingles vaccine: live attenuated vaccine and inactivated vaccine (genetic recombination). A live attenuated vaccine is a vaccine in which part of the virus or bacteria that causes a disease has been modified to retain the ability to self-reproduce and induce immunity, but the ability to cause toxicity has been removed. Vaccination is contraindicated in patients undergoing chemotherapy or receiving immunosuppressive therapy including chemotherapy or high-dose steroids, so vaccination is restricted in some breast cancer patients.
Genetically recombinant shingles vaccine, available for immunocompromised patients such as cancer patients
On the other hand, inactivated vaccines (genetic recombination) can also be administered to people with weakened immunity, including cancer patients. Immunogenicity and safety were demonstrated in several clinical studies conducted on adult solid tumor patients receiving anticancer treatment. The U.S. Centers for Disease Control and Prevention (CDC) recommends that immunosuppressed or compromised adults 19 years of age or older receive an inactivated vaccine to prevent shingles.
In Korea, according to the recently revised guidelines of the Korean Society of Infectious Diseases, adults aged 50 years or older as well as those aged 18 years or older who are at high or expected to be at high risk of shingles due to decreased immunity or immunosuppression due to disease or treatment and those with severe immunity Vaccination with inactivated vaccines is recommended for those at risk (autologous hematopoietic stem cell transplant recipients, solid cancer, blood cancer, solid organ transplant patients, etc.).
Professor Jeong emphasized, “It is important to prevent shingles and complications caused by herpes zoster, as they can further lower the quality of life of breast cancer patients who are tired of long-term treatment and management.” He said, “As an inactivated vaccine with proven immunogenicity and good safety for solid cancer patients has been released in Korea, we recommend that people with breast cancer and other diseases consult with their doctor and get the preventive vaccine to protect themselves from shingles. “He said.
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