The scientists conducted their experiments on mice suffering from a type of brain cancer called glioblastoma, according to a newspaper "The Independent" British.
On the study and its importance, lead author Khalid Shah said: "using Gene engineeringWe repurpose cancer cells to develop a treatment that destroys infected cells and stimulates the immune system immunity to destroy tumors in their initial stages, and cancer prevention".
Shah added: "This breakthrough raises hopes that the DNA in the brain could be modified with a vaccine, without the need to remove any tissue".
According to the revolutionary experiment, which was published in the journal Science Translational Medicine, the technology that was tried takes advantage of the technology "CRISPR" which act as molecular scissors, cut DNA at specific sites, and either deletes sections or replaces them with alternative sequences that secrete a protein that attaches to the target.
It is worth noting that about 2,500 cases are diagnosed Glioblastoma In the United Kingdom every year, only 7 percent of them survive, knowing that the only treatment for this disease is surgery and medications with many side effects.
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And the treatment kills tumors in the brainAnd it trains the immune system to prevent a recurrence, by releasing a gene-editing tool called CRISP-CAS9 that destroys proteins. cancer.
The scientists conducted their experiments on mice suffering from a type of brain cancer called glioblastoma, according to the British newspaper, The Independent.
On the study and its significance, lead author Khalid Shah said: “Using Gene engineeringWe repurpose cancer cells to develop a treatment that destroys infected cells and stimulates the immune system immunity to destroy tumors in their initial stages, and cancer prevention“.
“This breakthrough raises hopes of modifying the DNA in the brain with a vaccine, without the need to remove any tissue,” Shah added.
According to the revolutionary experiment, whose details were published in the journal Science Translational Medicine, the technology that was tested takes advantage of the “CRISPR” technology, which acts as a molecular scissors, cutting DNA at specific sites, and either deletes sections or replaces them with alternative sequences that secrete a protein that attaches to the target.
It is worth noting that about 2,500 cases are diagnosed Glioblastoma In the United Kingdom every year, only 7 percent of them survive, knowing that the only treatment for this disease is surgery and medications with many side effects.