Cell Biology

O-Acetylrubiarbonol B Induces Colorectal Cancer Cell Apoptosis via JNK/p38 MAPK and ROS

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O-Acetylrubiarbonol B induces apoptosis in colorectal cancer cells by driving reactive oxygen species generation and activating JNK and p38 MAPK pathways, according to findings published in Nature. This research joins … Read More

AI Tool Predicts Personalized Cancer Drug Responses Using Single-Cell Data

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Artificial intelligence models can now predict patient responses to breast-cancer drugs by analyzing single-cell RNA sequencing data from tumor clones. Developed by researchers at the National Cancer Institute, the computational … Read More

New Base Editing Techniques Accurately Modify Genes in Human Embryos, But Risks Remain

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Published on September 9, a study detailed in Nature by Columbia University researchers reveals that advanced base editing techniques can accurately modify single-letter DNA mutations in human embryos. Led by … Read More

Cord Blood Stem Cell Transplant Risks and Foscarnet Effects on HHV-6

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Mycophenolate mofetil-based prophylaxis in allogeneic hematopoietic stem cell transplantation shows no statistically significant difference in acute graft-versus-host disease incidence compared to methotrexate-based regimens, according to a systematic review. However, clinical … Read More

New Genetic Vulnerability Discovered in Acute Myeloid Leukemia

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Acute myeloid leukemia (AML) research has advanced significantly following a recent discovery by biomedical investigators detailing a previously unknown genetic vulnerability within malignant cells. Published in peer-reviewed literature, this finding … Read More

Blood Volume and Red Blood Cell Concentration in Critically Ill Patients: A Review of Clinical Studies

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Researchers have confirmed that allogeneic hematopoietic stem cell transplantation (HSCT) remains a viable, curative strategy for children with myeloid malignancies, despite significant challenges in disease management. By utilizing healthy donor … Read More