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BCNatal, symbol of the new era of maternal-fetal medicine

by archyde

Much of the quality of life that a person will be able to enjoy throughout their lives is gestated in the womb. That is why prenatal life is a fundamental stage for the development of the different components of the human body. However, around…


Much of the quality of life that a person will be able to enjoy throughout their lives is gestated in the womb. That is why prenatal life is a fundamental stage for the development of the different components of the human body. However, around 2-3% of pregnancies show some important problem that can affect the fetus directly or indirectly, and around 10-15% will require some type of care.

It is estimated that between 7-10% of newborns arrive in the world with low birth weight. The most serious cases affect 0.5%. Despite the fact that in recent decades there have been important advances in the medical management of these children, there is still much to be done, taking into account that the mortality rates in these patients are still high, beyond 25%. They are babies who, at the moment, cannot be provided with optimal results, so very precise solutions must be thought of to improve their quality of life.

Therefore, reducing the prevalence and severity of different ailments that can develop in adults related to neurological, cardiovascular and pulmonary consequences of prenatal origin is one of the main objectives of maternal-fetal medicine.

In the face of high complexity, it is essential to have a very high resolution diagnostic capacity. This is achieved thanks to monographic units made up of specialists dedicated to the in-depth study of fetal pathology, with high precision for both diagnosis and treatment. This is precisely what the BCNatal Fetal Medicine Research Center offers, an internationally recognized university and multidisciplinary research center in fetal and perinatal medicine, linked to the Hospitals Clínic and Sant Joan de Deu, and the University of Barcelona.


Reference in fetal medicine

The main mission of this center, currently considered an important international benchmark, is to identify methods of diagnosis and early treatment of diseases of prenatal origin that have an impact on childhood and adult life.

Dr. Eduard Gratacós, current director of the BCNatal Fetal Medicine Research Center, has been the promoter of the Fetal and Perinatal Medicine research group, having managed over the years to consolidate a scientific research model of excellence based on efficiency, multidisciplinarity and innovation.

The center has a high translational capacity thanks to a multidisciplinary team made up of around 450 professionals. Among them, doctors specializing in fetal medicine, cardiology, neurodevelopment and reproductive medicine, as well as experts in biology, pharmacy, bioengineering, epidemiology and statistics.

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Health

[Melancholic Brain]Treatment of Depression in the Elderly (1) | Fanggezi vocus

by archyde
Treatment of geriatric depression requires individualized assessment. (Photo: Edward Blanco on Unsplash)

Author: Jian Wanxi, a psychiatrist

Release date: 2022/09/02

This article is based on the experience of in-office whispers, cognitive behavioral therapy, and mindfulness-based cognitive psychotherapy in a psychiatric outpatient clinic. All conversations have been rewritten to remove all descriptions that could identify specific identities. If there is a coincidence, please do not be seated.

The treatment of senile depression is different from that of general adult depression in terms of drug selection and treatment selection, and requires individual evaluation. In this article, let’s take a look at what treatments are available and what issues should be paid attention to during treatment.

The treatment dilemma of senile depression

Unlike general adult depression, late-life depression (LLD) has a poor response to drug therapy and non-drug therapy, is prone to co-morbid physical diseases, and also affects each other. (Extended reading: “[Melancholic Brain]What is geriatric depression?》）

Clinically, when using drugs to treat senile depression, considering the burden of liver and kidney function, drug side effects, risk of falling, and impact on cognitive function, it is often necessary to slowly increase the drug from low doses to ensure safety. Even if the treatment is in the right direction and the drug is effective, the response to the treatment of senile depression is slow. Patients often doubt whether the drug treatment is effective, and patients and their families often lack the tolerance to stop continuing treatment.

Different treatment methods and therapeutic effects of senile depression

Basically, we can divide the treatment of geriatric depression into five types: drug therapy, psychotherapy, life and behavior therapy, diet and nutrition, and non-invasive brain stimulation therapy.

Pharmacological treatment of senile depression

Drug treatment is based on selective serotonin recovery inhibitors (SSRIs) and serotonin norepinephrine recovery inhibitors (SNRIs), and SARS antidepressants are second-line drugs. SSRIs and SNRIs are safe to use in older adults.

In the treatment of senile depression, antidepressant drugs should be started at low doses, so as to avoid too strong side effects, which would make patients intolerable and affect the compatibility of treatment. Complete drug treatment is at least six months after the symptoms of depression are relieved. If depression recurs or cannot be relieved, drug treatment may take longer. Stopping the medication early increases the chance of a depression relapse.

It is worth noting that nearly 1/3 of the elderly depression is drug-resistant major depression. Possible reasons include: (1) Insufficient dose of depression drugs, but the dose cannot be increased due to drug side effects; (2) There are many interactions with other drugs, and there are not many drug choices, and falls should be avoided; (3) Objective conditions such as external environment, aging, The mental state, physical health, nutritional status or disability state cannot be completely changed, improved or overcome; ④The mental state cannot be changed or treated, etc.

In addition, compared with young people, the elderly are often accompanied by many physical ailments, take multiple drugs, have many interactions with depression drugs, and have less room for drug choices. During drug treatment, the principles of fewer types of drugs, low doses, slow adjustment, and avoidance of falls or drug side effects are the principles.

Psychotherapy of senile depression

Among the psychotherapy techniques, cognitive-behavioral psychotherapy is the preferred treatment method, and other psychotherapies include psychoanalysis, supportive psychotherapy, nostalgic groups, narrative therapy, and mindfulness-based cognitive-behavioral therapy.

Psychotherapy mainly focuses on dealing with the depressed mood of elderly patients with depression and melding the meaning of life in elderly patients. If the patient has strong anger and resistance, the effect of psychotherapy will be greatly reduced. Geriatric depression is less responsive to psychotherapy than depression that develops in adolescence or adulthood.

However, in the treatment of senile depression, we cannot rely on drugs alone. The more psychological issues of senile depression patients, the worse the treatment response of drug therapy alone without psychotherapy.

Life and Behavior Therapy for Depression in the Elderly

Regular work and rest (sunshine rules), not lying in bed during the day, regular aerobic exercise, mindfulness practice and increasing social interaction (in addition to friends you met when you were young, church activities, community colleges, and neighborhood activities, you can also consider participating in the C of Long-term Care 2.0 Activities related to long-term care stations in high-level alleys) can help prevent and treat senile depression.

Regular work and rest and sunshine rules are very important. With the increase of age, the secretion of melatonin in the brain gradually declines at night, which affects the circadian rhythm. It is easy to sleep lightly and have many dreams. Even turning on the night light or operating the mobile phone may affect sleep. If there is sufficient light during the day (especially in the early morning, it is recommended to be in the sun for at least 1~2 hours), reduce the light before going to bed at night and reduce the stimulation of the light source of 3C products, which will help the mind to judge when to rest.

(To be continued)

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Health

The 20-year-old Barcelona academy player was killed..and escaped

by archyde

The Barca Residency Academy, associated with Barcelona, ​​​​ announced the tragically death of the young player, Carter Payne, at the age of twenty, after he was hit by a car in the city of Statesboro in the Republic of Georgia, and its driver fled.
“We are devastated by the tragic loss of one of our students, Carter Pine. He was an extraordinary brother, teammate and student-athlete who will be greatly missed. We send our love and support to his family and friends at this very difficult time.”
According to local media, the soccer player was riding an electric scooter near the campus of Georgia Shutter University when he was hit by an SUV, the driver of which escaped, so he was flown to Memorial Health Hospital, but he soon died.

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Health

Diabetes increases mortality in COVID-19

by archyde

news

Also obesity and high blood pressure

by Michael Richter

(17.05.2022) Obesity, impaired blood sugar metabolism and high blood pressure increase the risk of dying from COVID-19 in young adults and middle-aged people between 18 and 55 years of age to a level that is otherwise only observed in older people. This is shown by a current study based on data from the European case registry for patients with SARS-CoV-2 infection (LEOSS).

The German Center for Diabetes Research (DZD) and the German Diabetes Society (DDG) see the results as an incentive to continue to focus on prevention in the fight against non-communicable diseases such as diabetes. They point out that older people, and especially men, are at particularly high risk of becoming seriously ill and dying from COVID-19. Obesity and elevated blood sugar levels are also considered potential risk factors for severe COVID-19 courses. However, the effect that several previous illnesses in combination have on the course of a SARS-CoV-2 infection has not yet been sufficiently investigated in Germany.

In order to find out whether obesity, diabetes and high blood pressure influence the severity of COVID-19 disease and increase the associated mortality, researchers from, among others, the German Center for Diabetes Research (DZD), the IDM (Institute for Diabetes Research and Metabolic Diseases). from Helmholtz Munich at the Eberhard-Karls-Universität Tübingen), and the German Center for Infection Research (DZIF), evaluated data from a total of 3,163 patients with a SARS-CoV-2 infection from the European case registry LEOSS2.

“It was shown that obesity, a disturbed blood sugar metabolism and high blood pressure have an additive effect on COVID-19-related mortality – especially in comparatively younger patients aged between 18 and 55 years,” explains Professor Dr. medical Norbert Stefan, first author of the study. The study also concluded that people in this age group with all three pre-existing conditions have a similar increased risk of death as older people (56-75 years) who were metabolically healthy and not obese. “This finding has an immense impact on how we deal with the SARS-CoV-2 infection and the so-called widespread diseases, because so far many of those affected assumed that being younger largely protects against a serious infection with COVID-19,” says Stefan.

“It is therefore particularly important to intensify medical monitoring and therapy for younger COVID-19 patients. Especially if you are overweight, have diabetes or high blood pressure,” says the last author of the study, Professor Dr. medical Andreas Birkenfeld, medical director of the Medical Clinic IV of the University of Tübingen, head of the IDM and spokesman of the DZD. Based on their many years of knowledge about the important role of obesity and a disturbed metabolic situation in the development of serious diseases, Stefan, Birkenfeld and colleagues pointed out these risks early on in the course of the COVID-19 pandemic.

The COVID-19 pandemic thus clearly shows that it is important for politicians to implement far-reaching preventive measures. This also includes promoting plans for the further development of the Prevention Protection Act in order to counteract the advance of non-communicable diseases such as diabetes, high blood pressure and obesity. “Politics must create framework conditions that make health-promoting behavior possible and change the conditions in relation to exercise and nutrition in such a way that all German citizens benefit from them,” says Professor Dr. medical Andreas Fritsche, Vice President of the DDG from the Institute for Diabetes Research and Metabolic Diseases at Helmholtz Munich at the University of Tübingen.

“This includes, in particular, targeted individual preventive measures for high-risk populations, as we recently demonstrated in the Prediabetes Lifestyle Intervention Study (PLIS).” Wherever technical expertise is needed for the implementation of future projects, the DDG and the DZD and you are there Network of science, doctors, consulting professions and patient associations available as discussion partners.

About the LEOSS study:

On the initiative of the German Society for Infectious Diseases (DGI), a European case register was set up together with the German Center for Infection Research (DZIF), in which clinical data for patients with SARS-CoV-2 infection is collected. LEOSS is a European non-interventional multicenter cohort study. Launched in March 2020, the registry is characterized by the fact that all collected data goes to the scientific community for joint analysis. The German Centers for Health Research (DZG) are also involved in the register. The DZD uses the register, for example, to investigate the influence of obesity and a disturbed metabolism on the severity of a COVID-19 disease.

About the German Center for Diabetes Research (DZD) eV:

The German Center for Diabetes Research (DZD) eV is one of the six German centers for health research. It brings together experts in the field of diabetes research and combines basic research, epidemiology and clinical application. The aim of the DZD is to make a significant contribution to the successful, tailor-made prevention, diagnosis and therapy of diabetes mellitus using a new, integrative research approach.

Members of the network are the Helmholtz Munich – German Research Center for Health and the Environment, the German Diabetes Center DDZ in Düsseldorf, the German Institute for Human Nutrition DIfE in Potsdam-Rehbrücke, the Institute for Diabetes Research and Metabolic Diseases at Helmholtz Munich on the Eberhard-Karls -University of Tübingen and the Paul Langerhans Institute Dresden of the Helmholtz Munich at the University Hospital Carl Gustav Carus of the TU Dresden, associated partners at the universities in Heidelberg, Cologne, Leipzig, Lübeck and Munich as well as other project partners. Further information: www.dzd-ev.de

About the German Diabetes Society (DDG):

With more than 9200 members, the German Diabetes Society (DDG) is one of the largest medical and scientific specialist societies in Germany. It supports science and research, is involved in further education and training, certifies treatment facilities and develops guidelines. The aim is more effective prevention and treatment of the widespread disease diabetes, which affects more than eight million people in Germany. To this end, it also undertakes extensive health policy activities.

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Entertainment

Ghada Abdel Razek is very elegant in her latest looks (photo)

by archyde

Egyptian actress Ghada Abdel Razek published a new photo of her on her personal account on the social networking site “Instagram”, with her latest photo session.

Ghada Abdel Razek appeared with a soft look, wearing a distinctive black dress, leaving her tufts of hair hanging over her shoulders.

The photo won the admiration of a large number of her followers, and many closed the photo, expressing their love for her and praising her elegance.

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world

American brand with ‘Adult Only’ ice cream; Why only for adults?

by archyde
When we hear the word ice cream, we are greedy for ages. Kids’ joy knows no bounds, especially when they get ice cream. But the famous ice cream brand Hogan-Das has introduced an ice cream flavor that can only be eaten by adults. This taste is made especially for adults only, because things are a little different than usual when eating this ice cream.

Hagen Das thus introduced two new different flavors to the market. Both are a little different from regular ice creams. The company has used alcohol in both of these flavors. According to a report in the Daily Mail, the company is introducing these flavors only to adults from their cocktail collection. These adult-only flavors are planned to be released during London Cocktail Week.

Rum caramel is another flavor combination that combines Irish whiskey and chocolate waffle.
People may feel a little intoxicated after eating these ice creams, but things are not going to get any worse. Rum and whiskey flavored ice creams contain less than 0.5% alcohol per serving. A box can cost around Rs.500. Both flavors are available in different sizes.

Also Read- Unable to bear the joy, the young woman danced at the ATM counter; Video goes viral

Prior to this, the Hagen-Dass Spirit Collection was released in 2020 and received great acclaim. The rose and cream flavor of the American ice cream brand is very popular. Hagen-Das was started in 1960 in New York City by Ruben and Rose Matos. The company initially made ice cream in three flavors: vanilla, chocolate and coffee. But now Hagen-Dass has become a leading brand. Ice cream lovers are waiting for the new flavors of Hagen-Dass. It costs around Rs 500 per box. All flowers are available in normal size and small size.

In 2020, the ice cream introduced by the company will include four different flavors with one-third fewer calories than regular ice cream. There are just 210 to 230 calories per serving in the collection compared to traditional flavors up to 380 calories.
There are a lot of fans for this new experiment in ice cream. Kids who love ice cream are waiting for other innovative ice cream experiments.

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